Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11089576 | 0.99 | ALDH1A1 (0.48) | ALDH1A1RAB9AGFERSMN1; SMN2MAPT | |
| SCHEMBL6864372 | 0.91 | ALDH1A1 (0.44) | ALDH1A1RAB9AGFERSMN1; SMN2MAPT | |
| SCHEMBL7503188 | 0.87 | ALDH1A1 (0.44) | ALDH1A1RAB9AGFERSMN1; SMN2MAPT | |
| SCHEMBL11094224 | 0.84 | GAA (0.50) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11093421 | 0.83 | MAPT (0.49) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11090089 | 0.81 | RECQL (0.43) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL6342412 | 0.77 | GAA (0.54) | ATMLMNAHIF1AGAA | |
| SCHEMBL21835172 | 0.76 | TRPV6 (0.58) | ALDH1A1RAB9AGFERSMN1; SMN2MAPT | |
| SCHEMBL6862148 | 0.74 | ALDH1A1 (0.58) | ALDH1A1RAB9AGFERSMN1; SMN2MAPT | |
| SCHEMBL12158713 | 0.73 | ALDH1A1 (0.53) | ALDH1A1RAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479958-A | Methods and compositions for inhibiting herpes virus using pyridinyl ketones | THE DOW CHEMICAL COMPANY (US) | 1984-10-30 | — | — | US | disclosed |