Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090303 | 0.80 | KDM4E (0.47) | EGFR | |
| SCHEMBL11091059 | 0.76 | EGFR (0.49) | MAOBPARP1HRH3EGFRPARP10 | |
| SCHEMBL7907691 | 0.71 | MAOB (0.73) | MAOBPARP10SIRT2PARP15 | |
| SCHEMBL3454792 | 0.71 | PARP15 (0.62) | MAOBPARP1PARP10SIRT2ALOX5 | |
| SCHEMBL4819103 | 0.71 | MAOB (0.59) | MAOBALOX5 | |
| SCHEMBL162815 | 0.70 | PARP10 (0.60) | MAOBPARP10SIRT2ALOX5PARP15 | |
| SCHEMBL6140955 | 0.70 | PARP15 (0.75) | MAOBPARP10SIRT2PARP15 | |
| Lithium Ion SCHEMBL29695998 | 0.69 | MAOB (0.57) | MAOBALOX5 | |
| SCHEMBL6605312 | 0.68 | HTR2C (0.47) | SLC6A4 | |
| SCHEMBL30848304 | 0.68 | PARP1 (0.51) | PARP1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443603-A | PROTEOLYTIC ENZYME INHIBITORS | KOWA COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067561-A2 | Piperazine derivatives and processes for producing them | KOWA COMPANY, LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |