Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063207 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SLC6A2KMT2ASLC6A3MEN1 | |
| SCHEMBL10946417 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SLC6A2KMT2ASLC6A3GAA | |
| SCHEMBL24534624 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SLC6A2KMT2ASLC6A3GAA | |
| SCHEMBL25948326 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SLC6A2KMT2ASLC6A3GAA | |
| SCHEMBL21103823 | 0.84 | HSD17B10 (0.50) | HTR2CALDH1A1SLC6A4KMT2AHTR1A | |
| SCHEMBL25265146 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL22648518 | 0.83 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL25190840 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL12027622 | 0.83 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL13049037 | 0.83 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |