Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.57 |
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5299658 | 0.91 | ABCB1 (0.55) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL30892476 | 0.90 | MYC (0.55) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL7342938 | 0.90 | MYC (0.55) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL751415 | 0.89 | KMT2A (0.62) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL6813421 | 0.89 | ALDH1A1 (0.69) | ALDH1A1ABCB1MAPTKMT2AMEN1 | |
| SCHEMBL750245 | 0.88 | CTSV (0.63) | CTSVCTSLABCB1MAPTKMT2A | |
| SCHEMBL965943 | 0.86 | ALDH1A1 (0.63) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL16004968 | 0.86 | ABCB1 (0.59) | CTSVCTSLABCB1MAPTKMT2A | |
| SCHEMBL9658186 | 0.86 | CTSV (0.58) | CTSVCTSLALDH1A1ABCB1MAPT | |
| SCHEMBL750963 | 0.86 | CTSV (0.58) | CTSVCTSLALDH1A1ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457872-A | IMMUNOREGULATORY | Yamanouchi Pharmaceutical Co. (JP) | 1984-07-03 | — | — | US | disclosed |
| EP-0030436-B1 | 2-HYDROXYOXANILIC ACID DERIVATIVES AND SALTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0030436-A1 | 2-Hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-06-17 | — | — | EP | disclosed |