Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.65 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233780 | 0.85 | MAPT (0.62) | MEN1KMT2ALMNAHTTRAB9A | |
| SCHEMBL30640703 | 0.80 | EPHX1 (1.00) | EPHX1EPHX2P2RY1SLC2A1MEN1 | |
| SCHEMBL2683478 | 0.80 | EPHX1 (1.00) | EPHX1EPHX2P2RY1SLC2A1MEN1 | |
| SCHEMBL4548158 | 0.80 | KDR (0.90) | EPHX1EPHX2P2RY1SLC2A1KDR | |
| SCHEMBL9084605 | 0.77 | KDR (0.72) | EPHX1EPHX2P2RY1SLC2A1KDR | |
| SCHEMBL12443228 | 0.77 | MAPT (0.74) | EPHX1EPHX2P2RY1SLC2A1KDR | |
| SCHEMBL22125366 | 0.76 | SMARCA2 (0.82) | KDRSMARCA2SMARCA4IGF1RGAA | |
| Cloflucarban SCHEMBL28866649 | 0.75 | KDR (0.80) | EPHX1EPHX2P2RY1SLC2A1KDR | |
| SCHEMBL22103803 | 0.75 | KDR (0.70) | EPHX1EPHX2P2RY1SLC2A1KDR | |
| SCHEMBL11005058 | 0.75 | KDR (0.85) | EPHX1EPHX2KDRCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472583-A | AND CORRESPONDING ISOCYANATE; UREA, THIOUREA, GUANIDINE INTERMEDIATES; FUNGICIDES, BACTERICIDES | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |
| US-4331669-A | Fungicidal pyridyl arylureas, compositions containing them and method of controlling fungi and bacteria | DOW CHEMICAL COMPANY LIMITED, ENGLAND (GB) | 1982-05-25 | — | — | US | disclosed |