Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092001 | 0.85 | EPHX1 (0.65) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL11239583 | 0.85 | MAPT (0.52) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL4555008 | 0.82 | MAPT (0.78) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL4555003 | 0.80 | IDO1 (0.78) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL4555072 | 0.80 | LMNA (0.69) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL10217960 | 0.80 | MAPT (0.76) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL11085799 | 0.80 | CDK1 (0.53) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL11251035 | 0.75 | MAOA (0.59) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL4555026 | 0.74 | LMNA (0.75) | MAPTALDH1A1NPSR1L3MBTL1MEN1 | |
| SCHEMBL18196960 | 0.74 | MAPT (0.66) | MAPTALDH1A1NPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331669-A | Fungicidal pyridyl arylureas, compositions containing them and method of controlling fungi and bacteria | DOW CHEMICAL COMPANY LIMITED, ENGLAND (GB) | 1982-05-25 | — | — | US | claimed |