Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397011 | 0.81 | MYC (0.42) | KMT2ALTB4RDHODHPOLBLMNA | |
| SCHEMBL8413490 | 0.78 | SLC6A2 (0.42) | KMT2ADHODHALDH1A1KDM4EMEN1 | |
| 7-Chlorokynurenic Acid SCHEMBL29386783 | 0.76 | IGFBP3 (0.47) | KMT2ADHODHKMOPHLPP2POLB | |
| 7-Chlorokynurenic Acid SCHEMBL31238955 | 0.76 | IGFBP3 (0.47) | KMT2ADHODHKMOPHLPP2POLB | |
| 7-Chlorokynurenic Acid SCHEMBL157187 | 0.76 | IGFBP3 (0.47) | KMT2ADHODHKMOPHLPP2POLB | |
| 7-Chlorokynurenic Acid SCHEMBL20770380 | 0.75 | IGFBP3 (0.46) | KMT2ADHODHKMOPHLPP2POLB | |
| SCHEMBL377036 | 0.74 | KDM4E (0.36) | KMT2AKMOLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8127677 | 0.73 | POLB (0.47) | KMT2APOLBSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL27627920 | 0.73 | ALDH1A1 (0.43) | KMT2ADHODHKMOPOLBLMNA | |
| SCHEMBL12349843 | 0.72 | KMT2A (0.52) | KMT2ADHODHKMOPHLPP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060429-B1 | DICHLOROQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | disclosed |
| EP-0060429-A1 | Dichloroquinoline derivatives, their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1982-09-22 | — | — | EP | disclosed |