Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083127 | 0.80 | LTA4H (0.50) | LTA4HSRD5A2IDH1GRIN1GRIN2B | |
| SCHEMBL246373 | 0.76 | LTA4H (0.67) | LTA4HSRD5A2IDH1GRIN1GRIN2B | |
| SCHEMBL7178244 | 0.76 | LTA4H (0.67) | LTA4HSRD5A2IDH1GRIN1GRIN2B | |
| SCHEMBL10269397 | 0.74 | SRD5A2 (0.68) | LTA4HSRD5A2IDH1GRIN1GRIN2B | |
| SCHEMBL23098203 | 0.72 | SRD5A2 (0.70) | LTA4HSRD5A2GRIN1GRIN2BCALM1 | |
| SCHEMBL9906839 | 0.72 | SRD5A2 (0.70) | LTA4HSRD5A2GRIN1GRIN2BCALM1 | |
| SCHEMBL9680517 | 0.72 | ST14 (0.48) | LTA4HSRD5A2GRIN1GRIN2BALDH1A1 | |
| SCHEMBL19091743 | 0.71 | SRD5A2 (0.59) | LTA4HSRD5A2IDH1GRIN1GRIN2B | |
| SCHEMBL12199185 | 0.71 | KMT2A (0.50) | LTA4HSRD5A2IDH1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9816693 | 0.70 | SRD5A2 (0.58) | LTA4HSRD5A2IDH1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452795-A | MITICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |