Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680517 | 0.93 | ST14 (0.48) | LTA4HSRD5A2GRIN1GRIN2BPPARG | |
| SCHEMBL5028191 | 0.84 | LTA4H (0.52) | LTA4HPPARGMEN1NPC1RAB9A | |
| SCHEMBL29619541 | 0.81 | ST14 (0.41) | SRD5A2GRIN1GRIN2BST14IDH1 | |
| SCHEMBL9681696 | 0.80 | BACE1 (0.42) | LTA4HPPARGST14MEN1NPC1 | |
| SCHEMBL27509240 | 0.80 | CALM1 (0.52) | LTA4HIDH1ALDH1A1 | |
| SCHEMBL7178244 | 0.80 | LTA4H (0.67) | LTA4HSRD5A2GRIN1GRIN2BPPARG | |
| SCHEMBL246373 | 0.80 | LTA4H (0.67) | LTA4HSRD5A2GRIN1GRIN2BPPARG | |
| SCHEMBL11092258 | 0.80 | LTA4H (0.46) | LTA4HSRD5A2GRIN1GRIN2BIDH1 | |
| SCHEMBL8732491 | 0.78 | MAOA (0.68) | LTA4HSRD5A2GRIN1GRIN2BMEN1 | |
| SCHEMBL10269397 | 0.78 | SRD5A2 (0.68) | LTA4HSRD5A2GRIN1GRIN2BIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452795-A | MITICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |