Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 4/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098696 | 0.86 | CYP11B1 (0.44) | ABL1 | |
| SCHEMBL11096842 | 0.80 | NPC1 (0.43) | ABL1CCR6SCN10AKCNH2 | |
| SCHEMBL11095244 | 0.79 | CYP19A1 (0.50) | — | |
| SCHEMBL9886352 | 0.79 | SCN10A (0.38) | ABL1CCR6SCN10AKCNH2 | |
| SCHEMBL7189416 | 0.78 | CYP3A4 (0.42) | ABL1CCR6KCNH2 | |
| SCHEMBL69378 | 0.78 | CYP3A4 (0.42) | ABL1CCR6KCNH2 | |
| SCHEMBL17185918 | 0.77 | PRMT6 (0.42) | ABL1EPHX2NR1H4PRMT6SCN10A | |
| SCHEMBL15686090 | 0.75 | CCR6 (0.38) | ABL1CCR6KCNH2 | |
| SCHEMBL11433073 | 0.73 | CCR6 (0.43) | ABL1CCR6KCNH2 | |
| SCHEMBL12700338 | 0.72 | HDAC3 (0.46) | EPHX2NR1H4EPHX1CCR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109299-A2 | 1,1-Disubstituted-2-heterocyclic ethanol derivatives | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |