Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094528 | 0.97 | OPRM1 (0.42) | OPRM1OPRL1DRD3SLC6A2SLC6A4 | |
| Ethylene SCHEMBL10833583 | 0.93 | OPRM1 (0.50) | OPRM1OPRL1DRD3SLC6A4OPRD1 | |
| Ethylene SCHEMBL11092451 | 0.92 | OPRM1 (0.46) | OPRM1OPRL1DRD3SLC6A4OPRD1 | |
| SCHEMBL11068638 | 0.90 | OPRM1 (0.52) | OPRM1OPRL1DRD3SLC6A4OPRD1 | |
| Ethylene SCHEMBL11099465 | 0.90 | OPRM1 (0.42) | OPRM1DRD3SLC6A2SLC6A4MEN1 | |
| SCHEMBL11093314 | 0.89 | OPRM1 (0.48) | OPRM1OPRL1DRD3SLC6A4OPRD1 | |
| SCHEMBL11557913 | 0.87 | OPRM1 (0.43) | OPRM1DRD3SLC6A2SLC6A4MEN1 | |
| SCHEMBL11093463 | 0.87 | DRD3 (0.39) | OPRM1DRD3OPRD1 | |
| Ethylene SCHEMBL10832290 | 0.85 | OPRD1 (0.41) | OPRM1OPRL1SLC6A2SLC6A4MEN1 | |
| Ethylene SCHEMBL11557572 | 0.85 | OPRD1 (0.39) | OPRM1SLC6A2SLC6A4MEN1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | claimed |
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |