Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19453365 | 0.86 | RAB9A (0.65) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL8181258 | 0.85 | RAB9A (0.48) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11090716 | 0.84 | RAB9A (0.53) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL14185029 | 0.84 | RAB9A (0.47) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11363820 | 0.84 | ALDH1A1 (0.54) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL14590441 | 0.82 | RAB9A (0.48) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11083131 | 0.82 | RAB9A (0.51) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11088449 | 0.81 | RAB9A (0.50) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11091988 | 0.81 | ALDH1A1 (0.59) | RAB9ANPSR1MAPTNPC1ALDH1A1 | |
| SCHEMBL11082963 | 0.81 | RAB9A (0.50) | RAB9ANPSR1MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |