Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092090 | 0.85 | HSD17B10 (0.54) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL11087116 | 0.81 | HSD17B10 (0.50) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL7754027 | 0.79 | HSD17B10 (0.62) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL30096217 | 0.77 | POLB (0.64) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL756511 | 0.77 | POLB (0.64) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL4440485 | 0.77 | HSD17B10 (0.64) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL647041 | 0.75 | TSHR (0.71) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL11092178 | 0.75 | HSD17B10 (0.54) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL11091475 | 0.75 | HSD17B10 (0.50) | HSD17B10POLBALDH1A1CFTRTSHR | |
| SCHEMBL8624849 | 0.74 | HSD17B10 (0.60) | HSD17B10POLBALDH1A1CFTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469874-A | ALKYL THIOSALICYLATES | MONSANTO COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
| US-4283508-A | Fragrant prevulcanization inhibitors | MONSANTO COMPANY (US) | 1981-08-11 | — | — | US | disclosed |