Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.45 |
| ▸ | CDK9 | P50750 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089327 | 0.83 | MAPT (0.42) | MAPTPPARGPPARAPDK4KCNH2 | |
| SCHEMBL20993990 | 0.82 | MAPT (0.50) | MAPTCCNT1CDK9PPARGPPARA | |
| SCHEMBL7549123 | 0.81 | MAPT (0.49) | MAPTCCNT1CDK9PPARGPPARA | |
| SCHEMBL186070 | 0.78 | CCNT1 (0.52) | MAPTCCNT1CDK9PPARGPPARA | |
| SCHEMBL29580432 | 0.77 | PDK4 (0.67) | PDK4NAMPTGRM5GRM1 | |
| SCHEMBL4859866 | 0.77 | PDK4 (0.67) | PDK4NAMPTGRM5GRM1 | |
| SCHEMBL13801237 | 0.75 | TNKS (0.51) | MAPTCCNT1CDK9PPARGPPARA | |
| SCHEMBL11087646 | 0.74 | CNR1 (0.51) | MAPTQDPRNAMPT | |
| SCHEMBL11083906 | 0.74 | QDPR (0.45) | MAPTQDPRNAMPTKCNH2 | |
| SCHEMBL5547709 | 0.72 | QDPR (0.54) | QDPRTNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105397-A1 | Sulphuric indole derivatives | MERCK PATENT GmbH (DE) | 1984-04-18 | — | — | EP | disclosed |