Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092802 | 0.83 | MAPT (0.45) | MAPTPPARGPPARAPDK4KCNH2 | |
| SCHEMBL11087646 | 0.81 | CNR1 (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL23064245 | 0.80 | ALDH1A1 (0.48) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11083906 | 0.75 | QDPR (0.45) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2882861 | 0.75 | PDK4 (0.68) | PDK4CNR1 | |
| SCHEMBL30135250 | 0.75 | PDK4 (0.68) | PDK4CNR1 | |
| SCHEMBL23277150 | 0.69 | KDM4E (0.49) | MAPTLMNAHTTPPARGPPARA | |
| SCHEMBL23102107 | 0.67 | KDM4E (0.58) | MAPTLMNAHTTPPARGPPARA | |
| SCHEMBL23701853 | 0.67 | SCD (0.43) | MAPTLMNASCDSCD5CNR1 | |
| SCHEMBL22324761 | 0.66 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105397-A1 | Sulphuric indole derivatives | MERCK PATENT GmbH (DE) | 1984-04-18 | — | — | EP | disclosed |