Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 8/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814186 | 0.81 | YTHDC1 (0.39) | YTHDC1P2RY1 | |
| SCHEMBL9583411 | 0.77 | YTHDC1 (0.46) | YTHDC1P2RY1NPC1POLBCDK5 | |
| SCHEMBL11096314 | 0.77 | CDK5 (0.38) | CDK5CDK5R1 | |
| SCHEMBL10815472 | 0.76 | YTHDC1 (0.47) | YTHDC1NPC1POLBCDK5CDK5R1 | |
| SCHEMBL11121820 | 0.76 | HDAC1 (0.39) | CDK5CDK5R1 | |
| SCHEMBL9583290 | 0.73 | CDK5 (0.42) | P2RY1NPC1CDK5CDK5R1 | |
| SCHEMBL11099072 | 0.70 | CDK1 (0.38) | CDK5CDK5R1 | |
| SCHEMBL10818029 | 0.70 | HDAC1 (0.42) | YTHDC1 | |
| SCHEMBL9583883 | 0.69 | YTHDC1 (0.50) | YTHDC1P2RY1 | |
| SCHEMBL10814378 | 0.69 | CCNB2 (0.43) | YTHDC1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105135-A1 | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-di-0-substituted 1,3 dihydroxy-2-propoxymethyl) purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-11 | — | — | EP | disclosed |