Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 8/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092809 | 0.81 | YTHDC1 (0.41) | YTHDC1P2RY1 | |
| SCHEMBL10818020 | 0.77 | CDK5 (0.36) | P2RY1 | |
| SCHEMBL10817682 | 0.76 | HDAC1 (0.38) | ADORA3 | |
| SCHEMBL9583411 | 0.75 | YTHDC1 (0.46) | YTHDC1P2RY1ADORA3 | |
| SCHEMBL10814193 | 0.75 | P2RY1 (0.48) | YTHDC1P2RY1 | |
| SCHEMBL10815472 | 0.74 | YTHDC1 (0.47) | YTHDC1ADORA3 | |
| SCHEMBL9583883 | 0.71 | YTHDC1 (0.50) | YTHDC1P2RY1 | |
| SCHEMBL9583290 | 0.70 | CDK5 (0.42) | P2RY1 | |
| SCHEMBL10818085 | 0.70 | CDK1 (0.40) | — | |
| SCHEMBL10818029 | 0.68 | HDAC1 (0.42) | YTHDC1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105135-B1 | SUBSTITUTED 9-(1-0- OR 3-0-MONOSUBSTITUTED OR 1,3-DI-0-SUBSTITUTED 1,3 DIHYDROXY-2-PROPOXYMETHYL) PURINES AS ANTIVIRAL AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4609661-A | HERPES VIRUS | SYNTEX (U.S.A.) INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4556659-A | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1985-12-03 | — | — | US | disclosed |