Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11094764 | 0.99 | KDM4E (0.51) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11184790 | 0.95 | KDM4E (0.53) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11112154 | 0.80 | HPGD (0.46) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11102198 | 0.80 | KDM4E (0.46) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11090827 | 0.78 | ALDH1A1 (0.43) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL18608515 | 0.78 | TSHR (0.56) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11105472 | 0.77 | KDM4E (0.48) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL11093011 | 0.77 | RXFP1 (0.45) | KDM4EHPGDALDH1A1HSD17B10MAPT | |
| SCHEMBL11084888 | 0.76 | RXFP1 (0.42) | KDM4EHPGDGAAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11196585 | 0.75 | KDM4E (0.49) | KDM4EHPGDGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482557-A | 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-11-13 | — | — | US | disclosed |
| US-4367229-A | 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-01-04 | — | — | US | disclosed |
| US-4321377-A | ANALGESICS, TRANQULIZERS, ANTIARTHERISOSCLEROTIC AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-23 | — | — | US | disclosed |