Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112154 | 0.81 | HPGD (0.46) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL11090997 | 0.80 | KDM4E (0.47) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL11092995 | 0.80 | KDM4E (0.52) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL11089322 | 0.79 | KDM4E (0.46) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL11094764 | 0.79 | KDM4E (0.51) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL11184790 | 0.78 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL11105472 | 0.76 | KDM4E (0.48) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL18586636 | 0.74 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL11196585 | 0.74 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL18372237 | 0.73 | RIPK1 (0.42) | KDM4EHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461769-A | ANTIASTHEMIC AGENTS-PYRIDO(1,2-A)PYRIMIDINE COMPOUNDS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-07-24 | — | — | US | disclosed |
| US-4234586-A | ASTHMA; 9-HYDRAZONO-4H-PYRIDO(1,2A)PYRIMIDINE DERIVATIVES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1980-11-18 | — | — | US | disclosed |