Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | OTUD7B | Q6GQQ9 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090757 | 0.88 | OTUD7B (0.41) | KMT2AHTTOTUD7BMAPTSMN1; SMN2 | |
| SCHEMBL11094711 | 0.84 | P2RY1 (0.48) | KMT2AHTTMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11089367 | 0.80 | P2RY1 (0.41) | P2RY1GRM5NOTUM | |
| Hydrochloric Acid SCHEMBL11092564 | 0.79 | P2RY1 (0.46) | KMT2AHTTMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11095431 | 0.79 | AKT1 (0.38) | OTUD7BP2RY1NOTUM | |
| SCHEMBL11091616 | 0.79 | AKT1 (0.38) | KMT2AOTUD7BMEN1P2RY1NOTUM | |
| SCHEMBL11086598 | 0.78 | OTUD7B (0.39) | OTUD7BNOTUMHTR1A | |
| SCHEMBL1571912 | 0.78 | P2RY1 (0.53) | P2RY1 | |
| SCHEMBL11093235 | 0.74 | SLC18A3 (0.40) | OTUD7BALDH1A1P2RY1NOTUM | |
| SCHEMBL11089140 | 0.74 | OTUD7B (0.41) | OTUD7BNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477667-A | Spiro[indoline-3,4'-piperidine]s and related compounds | AMERICAN HOECHST CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4408050-A | Spiro(indoline-3,4'-piperidine) and related compounds | AMERICAN HOECHST CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4379932-A | Process for preparing spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1983-04-12 | — | — | US | disclosed |
| US-4379933-A | Process for preparing spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1983-04-12 | — | — | US | disclosed |
| US-4345081-A | Spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4307235-A | Spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |