Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159880 | 0.95 | LMNA (0.52) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL10884007 | 0.93 | LMNA (0.55) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL28684939 | 0.91 | LMNA (0.53) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL2129458 | 0.90 | TSHR (0.46) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL10419385 | 0.89 | LMNA (0.62) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL3930992 | 0.87 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL769184 | 0.87 | TSHR (0.47) | LMNATSHRALDH1A1TDP1MEN1 | |
| SCHEMBL3028731 | 0.87 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL3720851 | 0.87 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL545424 | 0.87 | LMNA (0.66) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444960-A | POLYESTER, POLYSULFONATE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
| US-4284549-A | COMPRISING A POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A BISPHENOL AN POLYPHENYLENE SULFIDE | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4187259-A | Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0007171-A1 | Polymer compositions, molded articles and films with improved hydrolytic stability | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4126602-A | THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-11-21 | — | — | US | disclosed |