Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182362 | 0.98 | LMNA (0.48) | TSHRLMNAGPR84PPARGPPARD | |
| SCHEMBL11159880 | 0.92 | LMNA (0.52) | TSHRLMNAALDH1A1TDP1MEN1 | |
| SCHEMBL10884007 | 0.90 | LMNA (0.55) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8155595 | 0.88 | EGLN1 (0.43) | TSHRAKR1B1LMNAGPR84PPARG | |
| SCHEMBL11093080 | 0.87 | LMNA (0.47) | TSHRLMNAALDH1A1TDP1MEN1 | |
| SCHEMBL10419385 | 0.86 | LMNA (0.62) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL114259 | 0.85 | FFAR4 (0.50) | TSHRAKR1B1LMNAGPR84PPARG | |
| SCHEMBL769294 | 0.84 | LMNA (0.66) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3930992 | 0.84 | LMNA (0.66) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3720851 | 0.84 | LMNA (0.66) | LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668951-B2 | Pharmaceutical compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2017-06-06 | — | — | US | claimed |
| US-9375390-B2 | Agricultural compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2016-06-28 | — | — | US | claimed |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-8598231-B2 | Flavoring agents containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2013-12-03 | — | — | US | claimed |
| US-20130210934-A1 | FLAVORING AGENTS CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | DuPont Run & Lyle Bio Products Company, LLC (US) | 2013-08-15 | — | — | US | claimed |
| US-8436046-B2 | Detergent composition containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2013-05-07 | — | — | US | claimed |
| US-8309116-B2 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2012-11-13 | — | — | US | claimed |
| US-20120071390-A1 | DETERGENT COMPOSITION CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2012-03-22 | — | — | US | claimed |
| WO-2011158102-A1 | CONTINUOUS PROCESS FOR THE PRODUCTION OF POLYESTER RESINS SUITABLE AS BINDERS FOR COMPATIBLE THERMOSETTING PAINTS ANS PAINTS BASED ON SAID POLYESTER RESINS | ALCEA - AZIENDA LOMBARDA COLORI E AFFINI S.R.L. (IT) | 2011-12-22 | — | — | WO | claimed |
| EP-1991515-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS FOR BIOMASS-DERIVED EXTRACTS FRAGRANCE CONCENTRATES, AND OILS | DuPont Tate & Lyle Bio Products Company, LLC (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2008123845-A2 | COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2008-10-16 | — | — | WO | claimed |
| US-20070213247-A1 | Detergent and liquid soap compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-13 | — | — | US | claimed |
| US-20070207939-A1 | Compositions comprising mono and di esters of biologically-based 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-06 | — | — | US | claimed |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070203276-A1 | Plasticizers comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE &LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203323-A1 | Food compositions comprising biologically-based biodegradable 1,3-propanediol esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| WO-2007095262-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2007-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071390-A1 | DETERGENT COMPOSITION CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | PHOSPHO1, ABHD11, DEGS1 | TSHR 4379/4885AKR1B1 621/4885LMNA 1750/4885 |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | DECR1, DECR2, HSD17B12 | TSHR 4727/4885AKR1B1 203/4885LMNA 3804/4885 |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BMP2, PGD, EBP | TSHR 4738/4885AKR1B1 1405/4885LMNA 1877/4885 |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, CYP3A43 | TSHR 4172/4885AKR1B1 653/4885LMNA 3913/4885 |
| US-20130210934-A1 | FLAVORING AGENTS CONTAINING BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS | ALDH1A3, ALDH1A1, ALDH18A1 | TSHR 3931/4885AKR1B1 493/4885LMNA 2649/4885 |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, HPD | TSHR 4644/4885AKR1B1 514/4885LMNA 3333/4885 |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | PBDC1, CUTA, EBP | TSHR 3598/4885AKR1B1 167/4885LMNA 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.