Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691733 | 0.87 | ALDH1A1 (0.44) | MTTPALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL15691695 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL11085900 | 0.80 | MTTP (0.39) | MTTP | |
| SCHEMBL17050271 | 0.80 | MTTP (0.39) | MTTPALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL7045213 | 0.80 | MTTP (0.39) | MTTPALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL17460359 | 0.80 | MTTP (0.39) | MTTPALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL10778132 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTITGA4 | |
| SCHEMBL15691728 | 0.78 | APEX1 (0.51) | ALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL17051237 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTITGA4APEX1 | |
| SCHEMBL16034612 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTITGA4APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452745-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0018076-B1 | 9-AMINOALKYLFLUORENES, PROCESS THEREFOR AND ANTIARRHYTHMIC FORMULATIONS THEREOF | ELI LILLY AND COMPANY (US) | 1983-09-21 | — | — | EP | disclosed |
| US-4382093-A | 9-Aminoalkylfluorenes | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4277495-A | FLUORENE 9-AMINOALKYL-9-CARBOXYLIC ACIDS OR ESTERS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| EP-0018076-A1 | 9-Aminoalkylfluorenes, process therefor and antiarrhythmic formulations thereof | ELI LILLY AND COMPANY (US) | 1980-10-29 | — | — | EP | disclosed |