SCHEMBL16034612

SCHEMBL16034612

CCOCC1(C(=O)OC)c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
ITGA4 P13612 1/20 0.41
HPGD P15428 3/20 0.38
POLB P06746 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HSD17B10 Q99714 2/20 0.38
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
PDK2 Q15119 3/20 0.36
ALOX12 P18054 1/20 0.36
THRB P10828 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
APEX1 P27695 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16035090 0.88 ALDH1A1 (0.39) ALDH1A1MAPTITGA4HPGDPOLB
SCHEMBL27971207 0.88 ALDH1A1 (0.40) ALDH1A1MAPTHPGDKDM4ELMNA
SCHEMBL16035376 0.85 MTTP (0.43) PDK2TDP1NPSR1
SCHEMBL16034976 0.85 ALDH1A1 (0.44) ALDH1A1MAPTITGA4HPGDPOLB
SCHEMBL2686052 0.84 THRB (0.38) ALDH1A1MAPTITGA4LMNAPDK2
SCHEMBL16034198 0.84 ALDH1A1 (0.38) ALDH1A1MAPTITGA4HPGDPOLB
SCHEMBL27971145 0.84 PDK2 (0.37) ALDH1A1MAPTKDM4EPDK2THRB
SCHEMBL2685891 0.83 THRB (0.37) ALDH1A1MAPTITGA4PDK2THRB
SCHEMBL17051237 0.82 ALDH1A1 (0.46) ALDH1A1MAPTITGA4HPGDPOLB
SCHEMBL15691695 0.82 ALDH1A1 (0.46) ALDH1A1MAPTITGA4HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8933180-B2 Internal and external donor compounds for olefin polymerization catalysts IV BASF CORPORATION (US) 2015-01-13 US claimed
US-20140275451-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS IV BASF CATALYSTS LLC (US) 2014-09-18 US claimed
US-8933180-B2 Internal and external donor compounds for olefin polymerization catalysts IV BASF CORPORATION (US) 2015-01-13 US disclosed
US-20140275451-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS IV BASF CATALYSTS LLC (US) 2014-09-18 US disclosed