Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL11094432 | 0.91 | LMNA (0.57) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| Maleic Acid SCHEMBL11094426 | 0.91 | LMNA (0.57) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11096422 | 0.85 | PTGS1 (0.67) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11667770 | 0.85 | ADRB2 (0.88) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| Hydrochloric Acid SCHEMBL11115110 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11038848 | 0.80 | ADRB2 (0.64) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11094430 | 0.80 | KMT2A (0.44) | ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL7367812 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL8266174 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1CYP2D6ADRB3PTGS1 | |
| SCHEMBL11142317 | 0.79 | PTGS1 (0.64) | ADRB2ADRB1CYP2D6ADRB3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125315-A1 | PHENOXYAMINOPROPANOL DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-11-21 | — | — | EP | claimed |