Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597018 | 0.91 | MGLL (0.53) | ESR1MGLLESR2TLR9TDP1 | |
| SCHEMBL21888605 | 0.84 | ESR1 (0.48) | ESR1MGLLESR2ARKLF10 | |
| SCHEMBL11095584 | 0.79 | MGLL (0.42) | ESR1MGLLKLF10ALOX15ALOX12 | |
| SCHEMBL35285 | 0.78 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29360146 | 0.78 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29350788 | 0.78 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL8735072 | 0.77 | MGLL (0.42) | MGLLTLR9TDP1G6PDALDH1A1 | |
| SCHEMBL298974 | 0.76 | ESR1 (0.95) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29696084 | 0.76 | ESR1 (0.95) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL30474623 | 0.75 | ESR1 (0.62) | ESR1MGLLESR2ALOX12TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051687-B1 | MALEIMIDES AND PROCESS FOR THE PREPARATION OF SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-05-16 | — | — | EP | claimed |
| US-4400521-A | RESINS, VARNICHES, CURING AGENTS, LAMINATION, ADHESIVES, HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1983-08-23 | — | — | US | claimed |
| EP-0051687-A1 | Maleimides and process for the preparation of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-05-19 | — | — | EP | claimed |
| EP-0051687-B1 | MALEIMIDES AND PROCESS FOR THE PREPARATION OF SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-4400521-A | RESINS, VARNICHES, CURING AGENTS, LAMINATION, ADHESIVES, HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0051687-A1 | Maleimides and process for the preparation of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-05-19 | — | — | EP | disclosed |