Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093408 | 0.99 | L3MBTL1 (0.39) | L3MBTL1SMN1; SMN2CYP1A2MAPK1ALDH1A1 | |
| SCHEMBL11089411 | 0.93 | HRH3 (0.40) | L3MBTL1SMN1; SMN2CYP1A2MAPK1ALDH1A1 | |
| SCHEMBL11086481 | 0.90 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2CYP1A2MAPK1ALDH1A1 | |
| SCHEMBL11092055 | 0.89 | PAOX (0.38) | SMN1; SMN2ALDH1A1KDM4EHRH3DRD3 | |
| SCHEMBL11093762 | 0.88 | HRH3 (0.33) | SMN1; SMN2ALDH1A1HRH3POLBGAA | |
| SCHEMBL11087785 | 0.87 | SPHK1 (0.33) | HRH3 | |
| SCHEMBL2780336 | 0.75 | SPHK1 (0.33) | CYP1A2KDM4EPOLB | |
| SCHEMBL11097870 | 0.73 | ALDH1A1 (0.30) | SMN1; SMN2ALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL11092967 | 0.71 | NPSR1 (0.32) | — | |
| SCHEMBL11088489 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049779-B1 | 3-AMINOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |