Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098354 | 0.90 | MRGPRX4 (0.60) | MRGPRX4CYP4F2CYP4A11SMPD1ALDH1A1 | |
| SCHEMBL11094436 | 0.89 | CYP4A11 (0.76) | MRGPRX4CYP4F2CYP4A11SMPD1ALDH1A1 | |
| SCHEMBL10923937 | 0.81 | MRGPRX4 (0.50) | MRGPRX4CYP4F2CYP4A11SMPD1LMNA | |
| SCHEMBL10411878 | 0.81 | MRGPRX4 (0.77) | MRGPRX4SMPD1LOXL2CYSLTR1 | |
| SCHEMBL11097936 | 0.80 | CYP4A11 (0.64) | MRGPRX4CYP4F2CYP4A11SMPD1RAB9A | |
| SCHEMBL15061218 | 0.80 | MRGPRX4 (0.63) | MRGPRX4CYP4F2CYP4A11SMPD1ALDH1A1 | |
| SCHEMBL1122805 | 0.80 | MRGPRX4 (0.71) | MRGPRX4SMPD1LMNACYSLTR1 | |
| SCHEMBL10659025 | 0.79 | MRGPRX4 (0.74) | MRGPRX4 | |
| SCHEMBL28231008 | 0.79 | CYP4F2 (0.69) | MRGPRX4CYP4F2CYP4A11SMN1; SMN2TP53 | |
| SCHEMBL3489393 | 0.78 | ALDH1A1 (0.56) | MRGPRX4SMPD1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110405-A2 | Antiinflammatory/antiallergic compounds | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1984-06-13 | — | — | EP | disclosed |