Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490282 | 0.82 | PPM1D (0.49) | MRGPRX4CYP4F2CYP4A11LMNAHPGD | |
| SCHEMBL2499084 | 0.82 | KMT2A (0.53) | MRGPRX4MEN1KMT2ALMNAHPGD | |
| SCHEMBL11095166 | 0.81 | MRGPRX4 (0.63) | MRGPRX4CYP4F2CYP4A11LMNASMPD1 | |
| SCHEMBL19889483 | 0.81 | LMNA (0.44) | MRGPRX4MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL18105999 | 0.81 | LMNA (0.44) | MRGPRX4MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL10680301 | 0.81 | KDM4C (0.50) | MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL10677816 | 0.80 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL10684106 | 0.80 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL10682241 | 0.79 | MEN1 (0.48) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL11098354 | 0.79 | MRGPRX4 (0.60) | MRGPRX4CYP4F2CYP4A11SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181568-A2 | Anti-inflammatory/anti-allergic compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0110405-A2 | Antiinflammatory/antiallergic compounds | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1984-06-13 | — | — | EP | disclosed |