Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | PRKX | P51817 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537686 | 0.86 | ERBB2 (0.59) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL11084131 | 0.80 | ADORA1 (0.54) | ADORA1ADORA2AUSP8USP7USP47 | |
| SCHEMBL11084545 | 0.77 | KDM4E (0.55) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL19439626 | 0.77 | CHEK1 (0.59) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL11092132 | 0.77 | ADORA1 (0.55) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL15135221 | 0.77 | MEN1 (0.50) | ADORA1ADORA2AALDH1A1KDM4EHTT | |
| SCHEMBL12343920 | 0.76 | ERBB2 (0.53) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL14306925 | 0.76 | ERBB2 (0.53) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL18748047 | 0.76 | ADORA1 (0.61) | CHEK1ABL1PDGFRBPDGFRAFLT1 | |
| SCHEMBL16291602 | 0.75 | PGR (0.46) | CHEK1ABL1PDGFRBPDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56002970-A | — | — | None | — | — | JP | disclosed |
| JP-55115874-A | — | — | None | — | — | JP | disclosed |
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |
| JP-S562970-A | PREPARATION OF NOVEL 2,3-DICYANO-5-CHLOROPYRAZINE DERIVATIVE | KYOWA GAS CHEM IND CO LTD | 1981-01-13 | — | — | JP | disclosed |
| JP-S55115874-A | PREPARATION OF 2,3-DICYANO-5-HYDROXYPYRAZINE DERIVATIVE | KYOWA GAS CHEM IND CO LTD | 1980-09-06 | — | — | JP | disclosed |