Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | USP8 | P40818 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 2/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091380 | 0.84 | ADORA1 (0.56) | ADORA1ADORA2AADORA2BALOX15GSR | |
| SCHEMBL11095182 | 0.80 | CHEK1 (0.50) | ADORA1ADORA2AADORA2BUSP8USP7 | |
| SCHEMBL11366922 | 0.79 | ALOX15 (0.46) | ADORA1ADORA2AALOX15USP8USP7 | |
| SCHEMBL11411717 | 0.78 | ADORA1 (0.56) | ADORA1ADORA2AADORA2BALOX15GSR | |
| SCHEMBL28823023 | 0.76 | ADORA1 (0.66) | ADORA1ADORA2AADORA2BALOX15GRM5 | |
| SCHEMBL28949045 | 0.76 | ADORA1 (0.66) | ADORA1ADORA2AADORA2BALOX15GRM5 | |
| SCHEMBL11093293 | 0.76 | ADORA1 (0.60) | ADORA1ADORA2AADORA2BALOX15CTSS | |
| SCHEMBL11403339 | 0.76 | KDM4E (0.50) | ADORA1ADORA2AADORA2BALOX5KDM4E | |
| SCHEMBL11087127 | 0.73 | ADORA1 (0.51) | ADORA1ADORA2AADORA2BALOX15GSR | |
| SCHEMBL22239386 | 0.71 | ALOX5 (0.51) | ADORA1ADORA2AADORA2BALOX15GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55045647-A | — | — | None | — | — | JP | disclosed |
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |
| JP-S5545647-A | NOVEL 2,3-DICYANOPIRAZINE DERIVATIVE, ITS PREPARATION, AND HERBICIDE CONTAINING THE COMPOUND AS EFFECTIVE COMPONENT | KYOWA GAS CHEM IND CO LTD | 1980-03-31 | — | — | JP | disclosed |