Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090936 | 0.91 | BMPR1B (0.47) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11090062 | 0.91 | PDE4A (0.46) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11086404 | 0.90 | CYP1A2 (0.52) | HRH3GPR119ADRA2CSLC6A3CYP1A2 | |
| SCHEMBL11094260 | 0.89 | PDE4A (0.50) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL10647530 | 0.85 | PDE3B (0.51) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11088177 | 0.82 | BMPR1B (0.47) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11084934 | 0.81 | PDE3B (0.48) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11090645 | 0.81 | PDE4A (0.48) | HRH3BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL11087392 | 0.79 | CYP1A2 (0.50) | HRH3GPR119CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL11090751 | 0.77 | PDE3B (0.65) | HRH3GPR119ADRA2CSLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474785-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |