SCHEMBL11095199

SCHEMBL11095199

CCCCCC(N)C(N)CC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.55
CYP2D6 P10635 2/20 0.46
SPHK1 Q9NYA1 2/20 0.46
TP53 P04637 2/20 0.46
LMNA P02545 2/20 0.46
GMNN O75496 1/20 0.46
POLB P06746 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
BLM P54132 1/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
CETP P11597 1/20 0.46
HTT P42858 1/20 0.46
UBE2N P61088 1/20 0.46
LAP3 P28838 2/20 0.43
PLA2G1B P04054 1/20 0.41
PLA2G2A P14555 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576771 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL8075419 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL11088411 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL10813214 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL10813760 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL10809566 0.97 OPRM1 (0.52) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL27309929 0.95 OPRM1 (0.50) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL5050619 0.92 ALDH1A1 (0.46) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL615266 0.91 OPRM1 (0.63) OPRM1CYP2D6SPHK1TP53LMNA
SCHEMBL24017118 0.88 OPRM1 (0.60) OPRM1CYP2D6SPHK1TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3380538-A1 AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY Sika Technology AG (CH) 2018-10-03 EP disclosed
EP-3350245-A1 AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS Sika Technology AG (CH) 2018-07-25 EP disclosed
WO-2017089472-A1 AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY SIKA TECHNOLOGY AG (CH) 2017-06-01 WO disclosed
WO-2017046292-A1 AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2017-03-23 WO disclosed
EP-0036129-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLES BASF Aktiengesellschaft (DE) 1984-06-13 EP disclosed
EP-0036521-B1 PREPARATION OF 2-IMIDAZOLINES BASF Aktiengesellschaft (DE) 1983-10-19 EP disclosed
EP-0025191-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLES BASF Aktiengesellschaft (DE) 1983-05-25 EP disclosed
EP-0036519-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLE BASF Aktiengesellschaft (DE) 1983-03-02 EP disclosed
US-4340745-A Preparation of 2-imidazolines BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
US-4340744-A METAL OXIDES AS CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
EP-0036519-A1 Process for the preparation of imidazole BASF Aktiengesellschaft (DE) 1981-09-30 EP disclosed
EP-0036521-A1 Preparation of 2-imidazolines BASF Aktiengesellschaft (DE) 1981-09-30 EP disclosed
EP-0036129-A1 Process for the preparation of imidazoles BASF Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0025191-A1 Process for the preparation of imidazoles BASF Aktiengesellschaft (DE) 1981-03-18 EP disclosed
EP-0000208-B1 PROCESS FOR THE PREPARATION OF IMIDAZOLES BASF Aktiengesellschaft (DE) 1980-04-30 EP disclosed
EP-0000208-A1 Process for the preparation of imidazoles BASF Aktiengesellschaft (DE) 1979-01-10 EP disclosed