Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57524 | 0.87 | CA1 (0.63) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL29409606 | 0.87 | CA1 (0.63) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL31605318 | 0.87 | CA1 (0.63) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL1584839 | 0.85 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL1584838 | 0.85 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Acetamide SCHEMBL28617889 | 0.84 | CA2 (0.79) | CA1CA2CA9F2PRSS1 | |
| Dimethylamine SCHEMBL28365350 | 0.84 | CA1 (0.55) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL11485250 | 0.78 | HPRT1 (0.56) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL7729945 | 0.78 | CA1 (0.53) | CA1CA2CA9F2PRSS1 | |
| Diethylamine SCHEMBL28643757 | 0.78 | CA1 (0.49) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487725-A | Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-11 | — | — | US | disclosed |