SCHEMBL29409606

SCHEMBL29409606

O=S(=O)(Cl)c1cccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA9 Q16790 1/20 0.63
F2 P00734 3/20 0.52
PRSS1 P07477 3/20 0.52
PRSS2 P07478 3/20 0.52
PRSS3 P35030 3/20 0.52
HTR6 P50406 2/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PAX8 Q06710 1/20 0.46
HCRTR1 O43613 1/20 0.46
TSHR P16473 2/20 0.45
AKR1B1 P15121 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2A6 P11509 1/20 0.44
HPRT1 P00492 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31605318 1.00 CA1 (0.63) CA1CA2CA9F2PRSS1
SCHEMBL57524 1.00 CA1 (0.63) CA1CA2CA9F2PRSS1
SCHEMBL1584839 0.98 CA1 (0.61) CA1CA2CA9F2PRSS1
SCHEMBL1584838 0.98 CA1 (0.61) CA1CA2CA9F2PRSS1
Dimethylamine SCHEMBL28365350 0.92 CA1 (0.55) CA1CA2CA9F2PRSS1
SCHEMBL11485250 0.90 HPRT1 (0.56) CA1CA2CA9F2PRSS1
Acetamide SCHEMBL11095227 0.87 CA1 (0.55) CA1CA2CA9F2PRSS1
Pyridine SCHEMBL6537017 0.87 CA2 (0.50) CA1CA2CA9F2PRSS1
SCHEMBL3576602 0.86 CA1 (0.49) CA1CA2CA9F2PRSS1
SCHEMBL7729945 0.86 CA1 (0.53) CA1CA2CA9F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301859-A1 ENHANCED TARGETING USING ANTIBODY-OLIGONUCLEOTIDE CONJUGATES Code Biotherapeutics, Inc. (US) 2024-01-10 EP claimed
WO-2022187586-A1 ENHANCED TARGETING USING ANTIBODY-OLIGONUCLEOTIDE CONJUGATES CODE BIOTHERAPEUTICS, INC. (US) 2022-09-09 WO claimed
WO-2026100443-A1 RESIN, COMPOSITION, PHOTOCROSSLINKED PRODUCT, AND ELECTRONIC DEVICE COMPRISING SAME 東ソー株式会社 2026-05-15 WO disclosed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
WO-2025229046-A1 SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) 2025-11-06 WO disclosed
EP-4634226-A1 ANTIBODIES TO CUB DOMAIN-CONTAINING PROTEIN 1 (CDCP1) AND USES THEREOF Pheon Therapeutics Ltd (GB) 2025-10-22 EP disclosed
EP-4612186-A2 MONOCLONAL ANTIBODIES SPECIFIC FOR FAS LIGAND AND USES THEREOF Providence Health & Services - Oregon (US) 2025-09-10 EP disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 EP disclosed
CN-120065625-A Photoresist composition and preparation method and application thereof 中国科学院光电技术研究所 2025-05-30 CN disclosed
EP-4558479-A1 NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP disclosed
WO-2024216167-A1 COMPOSITIONS COMPRISING MODULATORS OF RIBONUCLEOPROTEIN GRANULE FORMATION AND DISSOLUTION AND METHODS OF USE THEREOF UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2024-10-17 WO disclosed
WO-2022184853-A1 ANTI-VSIG4 ANTIBODY OR ANTIGEN BINDING FRAGMENT AND USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2022-09-09 WO disclosed
EP-4048285-A1 TIM-3 INHIBITORS AND USES THEREOF Novartis AG (CH) 2022-08-31 EP disclosed
WO-2022165127-A2 TREATMENT OF INTEGRIN-RELATED DISORDERS WITH STAPLED PEPTIDES INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) 2022-08-04 WO disclosed
EP-4025606-A1 ANTI-VSIG4 ANTIBODY OR ANTIGEN BINDING FRAGMENT AND USES THEREOF Y-Biologics Inc. (KR) 2022-07-13 EP disclosed
WO-2022136838-A1 PLANT GROWTH PROMOTERS UNIVERSITY OF DURHAM (GB) 2022-06-30 WO disclosed
WO-2022139681-A1 METHODS FOR IDENTIFYING AND MONITORING INTERACTIONS OF PROTEIN WITH LIGAND AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-06-30 WO disclosed
WO-2022120048-A1 HDAC INHIBITORS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-06-09 WO disclosed
CN-114173880-A Methods of predicting cancer responsiveness to iron death induction therapy 纪念斯隆凯特琳癌症中心 2022-03-11 CN disclosed
EP-3959233-A1 NETRIN G1 AND NETRIN G1 LIGAND PEPTIDES AND ANTIBODIES AND USES THEREOF Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (US) 2022-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 CA1 740/4885CA2 1669/4885CA9 1059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.