Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089868 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL4021727 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL5007591 | 0.81 | HTT (0.38) | ALDH1A1HTTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL13082284 | 0.80 | CYP1A2 (0.44) | ALDH1A1HTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL302695 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2POLBCYP1A2 | |
| SCHEMBL4972108 | 0.79 | CYP1A2 (0.43) | ALDH1A1HTTPOLBCYP1A2CYP2C19 | |
| SCHEMBL2431935 | 0.79 | CYP1A2 (0.43) | ALDH1A1HTTPOLBCYP1A2CYP2C19 | |
| SCHEMBL11088824 | 0.77 | RAB9A (0.39) | ALDH1A1HTTSMN1; SMN2POLBCYP1A2 | |
| SCHEMBL13994207 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HTTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL4016442 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HTTKCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |