Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340875 | 0.82 | GAA (0.61) | ALDH1A1ADRA2BPTGS1TDP1GAA | |
| SCHEMBL1340914 | 0.81 | ALDH1A1 (0.63) | ALDH1A1ADRA2BPTGS1TDP1TSHR | |
| SCHEMBL29392357 | 0.80 | GAA (0.67) | ALDH1A1ADRA2BPTGS1TDP1SMN1; SMN2 | |
| SCHEMBL3684211 | 0.80 | GAA (0.67) | ALDH1A1ADRA2BPTGS1TDP1SMN1; SMN2 | |
| SCHEMBL8597510 | 0.80 | AR (0.58) | ALDH1A1TSHRSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL12474487 | 0.78 | TUBB4A (0.55) | ALDH1A1TDP1TSHRSMN1; SMN2TUBB4A | |
| SCHEMBL31522163 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ADRA2BPTGS1TDP1SMN1; SMN2 | |
| SCHEMBL1341128 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ADRA2BPTGS1TDP1TSHR | |
| SCHEMBL1339106 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ADRA2BPTGS1TDP1GAA | |
| SCHEMBL1340623 | 0.77 | ALDH1A1 (0.74) | ALDH1A1ADRA2BPTGS1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |