Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508252 | 0.85 | GAA (0.58) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL8444621 | 0.80 | GAA (0.58) | GAACDK1KCNJ6KCNJ3CYP1A2 | |
| SCHEMBL11090774 | 0.80 | GAA (0.49) | GAACDK1KCNJ6KCNJ3MAPT | |
| SCHEMBL11086619 | 0.79 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11089667 | 0.79 | TSHR (0.51) | GAACDK1KCNJ6KCNJ3KMT2A | |
| SCHEMBL10363991 | 0.78 | GAA (0.50) | GAACDK1KCNJ6KCNJ3CYP1A2 | |
| SCHEMBL10736294 | 0.77 | GAA (0.56) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL11086097 | 0.77 | GAA (0.56) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL28419963 | 0.76 | GAA (0.53) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL9021744 | 0.76 | GAA (0.53) | GAACDK1KCNJ6KCNJ3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023141-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, COMPOSITIONS CONTAINING THEM, INTERMEDIATES THEREFOR AND PREPARATION OF SUCH INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-11 | — | — | EP | disclosed |
| EP-0023141-A2 | Herbicidal sulfonamides, preparation and use thereof, compositions containing them, intermediates therefor and preparation of such intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |