Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272584 | 1.00 | FAAH (0.57) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL10639411 | 1.00 | FAAH (0.57) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL10633033 | 1.00 | FAAH (0.57) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL5249488 | 0.84 | CHRNB2 (0.40) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL2538589 | 0.84 | FAAH (0.41) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL11019265 | 0.84 | FAAH (0.55) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL22539940 | 0.83 | EPHX1 (0.53) | FAAHCNR1CNR2EPHX1ZDHHC7 | |
| SCHEMBL10636400 | 0.82 | FAAH (0.58) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL2537578 | 0.81 | FAAH (0.39) | FAAHCNR1CNR2NAAAEPHX1 | |
| SCHEMBL4923883 | 0.81 | FAAH (0.60) | FAAHCNR1CNR2NAAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048368-B1 | PROCESS FOR THE PREPARATION OF N- AND O-SUBSTITUTED MONO- OR BIS-URETHANES | BAYER AG (DE) | 1984-06-13 | — | — | EP | disclosed |
| EP-0048368-A2 | Process for the preparation of N- and O-substituted mono- or bis-urethanes | BAYER AG (DE) | 1982-03-31 | — | — | EP | disclosed |