Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170839 | 0.92 | CYP11B1 (0.43) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL11099754 | 0.92 | CYP11B1 (0.40) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL10532359 | 0.92 | TBXAS1 (0.48) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL11097478 | 0.91 | TBXAS1 (0.48) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL11098438 | 0.89 | HDAC1 (0.46) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL11168892 | 0.84 | TBXAS1 (0.48) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL11172124 | 0.84 | CYP11B1 (0.43) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL11167817 | 0.82 | MTNR1A (0.42) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B | |
| SCHEMBL11095806 | 0.77 | MTNR1A (0.48) | MTNR1AMTNR1BGNRHRTLR8TLR7 | |
| SCHEMBL11168702 | 0.74 | TBXAS1 (0.44) | CYP11B1CYP11B2TBXAS1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129051-A2 | Substituted indoles | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |