Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785972 | 0.93 | TSHR (0.66) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL2689893 | 0.93 | TSHR (0.65) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL2688287 | 0.93 | TSHR (0.65) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL18822943 | 0.93 | TSHR (0.65) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL18822989 | 0.93 | TSHR (0.65) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL18822941 | 0.93 | TSHR (0.65) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL757355 | 0.92 | TSHR (0.61) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL5739016 | 0.92 | TSHR (0.61) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL11122034 | 0.91 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL28846638 | 0.89 | TSHR (0.80) | TSHRTHRBNAAAPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425418-A | COLOR, CHARGE CONTROL, OLEFIN POLYMER, 1,3-PENTADIENE POLYMER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |