Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757355 | 1.00 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2688287 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18822943 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2689893 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18822989 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18822941 | 0.98 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL278570 | 0.96 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11096017 | 0.92 | TSHR (0.77) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17785972 | 0.91 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2880688 | 0.88 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409119-B1 | ASYMMETRIC GEL-FILLED MICROPOROUS MEMBRANES | UNIV MCMASTER (CA) | 2006-06-21 | — | — | EP | disclosed |
| US-6635104-B2 | Gas separation device | MCMASTER UNIVERSITY (CA) | 2003-10-21 | — | — | US | disclosed |
| US-20020104439-A1 | Gas separation device | MCMASTER UNIVERSITY (CA) | 2002-08-08 | — | — | US | disclosed |