Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15792781 | 0.85 | MAPT (0.50) | MAPTGAAALOX15POLBMAPK14 | |
| SCHEMBL27566029 | 0.82 | MAPT (0.50) | MAPTGAAALOX15POLBMAPK14 | |
| SCHEMBL951003 | 0.80 | KDM4E (0.48) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL11519197 | 0.79 | AKR1C3 (0.44) | MAPTGAAALOX15POLBALDH1A1 | |
| SCHEMBL27585830 | 0.79 | MAPT (0.50) | CHRM4MAPTGAAPOLBMAPK14 | |
| SCHEMBL28747892 | 0.79 | MAPT (0.50) | MAPTGAAALOX15POLBMAPK14 | |
| SCHEMBL19253323 | 0.78 | MAPT (0.53) | MAPTGAAALOX15POLBMAPK14 | |
| SCHEMBL28404725 | 0.77 | AKR1C3 (0.46) | CHRM4MAPTGAAALOX15MAPK14 | |
| SCHEMBL11215128 | 0.76 | MAPT (0.60) | MAPTGAAALOX15POLBMAPK14 | |
| SCHEMBL5079583 | 0.76 | AKR1C3 (0.48) | MAPTGAAALOX15POLBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044091-B1 | PROCESS FOR THE PREPARATION OF N-ALKYLAMINO-BENZOPHENONES | PIERRE FABRE S.A. (FR) | 1984-01-11 | — | — | EP | disclosed |
| EP-0010030-B1 | DERIVATIVES OF 2'-(ORTHO-CHLORO-BENZOYL),4'-CHLORO-GLYCIN ANILIDE, THEIR PREPARATION AND THEIR USE IN MEDICINES | PIERRE FABRE S.A. (FR) | 1982-05-05 | — | — | EP | disclosed |
| EP-0044091-A2 | Process for the preparation of N-alkylamino-benzophenones | PIERRE FABRE S.A. (FR) | 1982-01-20 | — | — | EP | disclosed |