SCHEMBL5079583

SCHEMBL5079583

O=C(c1ccccc1)c1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.48
ALDH1A1 P00352 4/20 0.48
ATM Q13315 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
GAA P10253 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NR4A1 P22736 1/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2C9 P11712 1/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.44
ALOX15 P16050 1/20 0.44
POLB P06746 1/20 0.43
MAPK13 O15264 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11519197 0.84 AKR1C3 (0.44) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL13645117 0.84 ALDH1A1 (0.56) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL6355098 0.83 CES2 (0.52) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL2987573 0.82 ALDH1A1 (0.50) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL8611314 0.81 LTA4H (0.43) ALDH1A1GAAMEN1KMT2AKDM4E
SCHEMBL5073237 0.81 ALDH1A1 (0.59) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL15792781 0.80 MAPT (0.50) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL7275952 0.80 MAPT (0.50) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL28747892 0.80 MAPT (0.50) AKR1C3ALDH1A1ATML3MBTL1TDP1
SCHEMBL9776268 0.80 HPGD (0.47) AKR1C3ALDH1A1ATML3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109763314-B UV-thermal dual-curing colored coating method for UHMPE fiber tows 山东鲁普科技有限公司 2021-11-19 CN claimed
WO-2021042251-A1 METHOD FOR PREPARATION OF POLYISOCYANATE BY PHOTOCHEMICAL REACTION AND METHOD FOR PREPARING WATERBORNE POLYURETHANE RESIN 万华化学集团股份有限公司 2021-03-11 WO claimed
WO-2001094452-A2 UV CURABLE COATING FOR GOLF BALLS LORD CORPORATION (US) 2001-12-13 WO claimed
US-20250052765-A1 Nanobody Discovery Platform and Related Methods CARNEGIE MELLON UNIVERSITY 2025-02-13 US disclosed
WO-2023111983-A1 NANOBODY DISCOVERY PLATFORM AND RELATED METHODS CARNEGIE MELLON UNIVERSITY (US) 2023-06-22 WO disclosed
CN-109763314-B UV-thermal dual-curing colored coating method for UHMPE fiber tows 山东鲁普科技有限公司 2021-11-19 CN disclosed
CN-112646461-A LED-UV (light-emitting diode-ultraviolet) photocureable nano-coating for piano surface and preparation method thereof 山东大学 2021-04-13 CN disclosed
EP-3150674-B1 ACTIVE ENERGY RAY-CURABLE COATING VARNISH, AND PRINTED MATTER USING SAME TOYO INK SC HOLDINGS CO LTD (JP) 2021-01-06 EP disclosed
CN-111295621-A Photosensitive resin composition, dry film and printed wiring board 互应化学工业株式会社 2020-06-16 CN disclosed
WO-2020045024-A1 PHOTOSENSITIVE RESIN COMPOSITION, DRY FILM AND PRINTED WIRING BOARD 互応化学工業株式会社 2020-03-05 WO disclosed
US-9783684-B2 Active energy ray-curable coating varnish, and printed matter using same TOYO INK SC HOLDINGS CO., LTD. (JP) 2017-10-10 US disclosed
CN-88100911-A Antihypercholesterolemic tetrazolium compounds 1988-09-28 CN disclosed
EP-0147299-B1 PROCESS FOR THE PREPARATION OF BENZOPHENONES RHONE-POULENC CHIMIE (FR) 1988-03-02 EP disclosed
US-4618726-A DEACTIVATED BENZENE COMPOUND WITH CARBONYL HALIDE IN LIQUID HYDROFLUORIC ACID AND BORON TRIFLUORIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-10-21 US disclosed
EP-0066543-B1 THERMALLY POLYMERIZABLE COMPOSITIONS AND PROCESS FOR THE THERMAL POLYMERIZATION OF CATIONICALLY POLYMERIZABLE COMPOUNDS CIBA-GEIGY AG (CH) 1985-11-27 EP disclosed
EP-0147299-A2 Process for the preparation of benzophenones RHONE-POULENC CHIMIE (FR) 1985-07-03 EP disclosed
US-4393185-A EPOXIDES CIBA-GEIGY CORPORATION (US) 1983-07-12 US disclosed
EP-0066543-A2 Thermally polymerizable compositions and process for the thermal polymerization of cationically polymerizable compounds CIBA-GEIGY AG (CH) 1982-12-08 EP disclosed
US-4207266-A CARBON TETRALIDE, HYDROGEN FLUORIDE, LEWIS ACID AD AROMATIC HYDROCARBON ROHM AND HAAS COMPANY (US) 1980-06-10 US disclosed
US-3956324-A THERMOPLASTIC POLYMER CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250052765-A1 Nanobody Discovery Platform and Related Methods CD2BP2, VAPB, VPS4B AKR1C3 4682/4885ALDH1A1 4771/4885ATM 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.