Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CD44 | P16070 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117347 | 0.86 | MAPT (0.60) | MAPTGAAPOLBMAPK14ALDH1A1 | |
| SCHEMBL11215128 | 0.86 | MAPT (0.60) | MAPTGAAPOLBMAPK14MAPK13 | |
| SCHEMBL10248660 | 0.86 | CHRM4 (0.44) | MAPTPOLBALDH1A1CD44LMNA | |
| SCHEMBL3664055 | 0.83 | MAPT (0.54) | MAPTGAAALDH1A1LMNAMEN1 | |
| SCHEMBL9061252 | 0.81 | ALDH1A1 (0.58) | MAPTGAAPOLBMAPK14MAPK13 | |
| SCHEMBL12304995 | 0.81 | PTGS1 (0.45) | MAPTGAAPOLBALDH1A1LMNA | |
| SCHEMBL5533149 | 0.80 | CD44 (0.56) | MAPTGAAPOLBALDH1A1CD44 | |
| SCHEMBL14916456 | 0.80 | MAPT (0.53) | MAPTGAAPOLBMAPK14MAPK13 | |
| SCHEMBL6055735 | 0.80 | MAPT (0.54) | MAPTGAAALDH1A1LMNAMEN1 | |
| SCHEMBL8033801 | 0.80 | MAPT (0.72) | MAPTGAAPOLBMAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419961-B1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10268053-B2 | UV/visible-absorbing vinylic monomers and uses thereof | NOVARTIS AG (CH) | 2019-04-23 | — | — | US | disclosed |
| EP-3419961-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | Novartis AG (CH) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017145022-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-08-31 | — | — | WO | disclosed |
| US-20170242274-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | ALCON INC. (CH) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10268053-B2 | UV/visible-absorbing vinylic monomers and uses thereof | VCL, UACA, XRCC6 | MAPT 132/4885GAA 2532/4885POLB 2981/4885 |
| US-20170242274-A1 | UV/VISIBLE-ABSORBING VINYLIC MONOMERS AND USES THEREOF | VCL, UACA, XRCC6 | MAPT 132/4885GAA 2532/4885POLB 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.