Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7896336 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10525004 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL11096099 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL3313005 | 0.90 | CA4 (0.50) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL8441974 | 0.90 | — | — | |
| Bicarbonate SCHEMBL28333171 | 0.89 | CA4 (0.46) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL30547294 | 0.86 | CA1 (0.36) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL28534382 | 0.86 | CA1 (0.36) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL2028638 | 0.84 | CA4 (0.42) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9442743 | 0.84 | CA4 (0.55) | CA4CA1FAHD1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235695-B1 | Cleaning agent with oligoammine activator complexes for peroxide compounds | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-22 | — | — | US | disclosed |