Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1425585 | 1.00 | CA2 (0.42) | CA2SLC34A1KDM4EMMP2THRB | |
| Iodide SCHEMBL28650690 | 1.00 | — | — | |
| Iodide SCHEMBL3851713 | 1.00 | — | — | |
| SCHEMBL88352 | 0.94 | — | — | |
| SCHEMBL634685 | 0.94 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| SCHEMBL2486859 | 0.94 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| SCHEMBL31402615 | 0.94 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| SCHEMBL8332638 | 0.89 | — | — | |
| Water SCHEMBL17318091 | 0.89 | — | — | |
| SCHEMBL7191422 | 0.89 | CA2 (0.42) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819656-B | A kind of graphene oxide/light-cured resin composite and its preparation method and application | 青岛科技大学 | 2017-06-23 | — | — | CN | disclosed |
| CN-106478902-A | A kind of photocurable resin material for casting | 湖南华曙高科技有限责任公司 | 2017-03-08 | — | — | CN | disclosed |
| EP-2280032-B1 | PHOTOPOLYMERIZABLE COMPOSITIONS | TOKUYAMA DENTAL CORP (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-8394869-B2 | Photopolymerizable compositions useful as a dental restorative material | TOKUYAMA DENTAL CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20110172323-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS | TOKUYAMA DENTAL CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2280032-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS | Tokuyama Dental Corporation (JP) | 2011-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172323-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS | RARA, RARB, RARG | CA2 3052/4885SLC34A1 4271/4885KDM4E 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.