Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096178 | 1.00 | POLB (0.38) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11096168 | 1.00 | POLB (0.38) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11096576 | 1.00 | POLB (0.38) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11097165 | 0.85 | RAB9A (0.43) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11097167 | 0.85 | RAB9A (0.43) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11097166 | 0.85 | RAB9A (0.43) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL11096748 | 0.85 | RAB9A (0.43) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL10977955 | 0.83 | L3MBTL1 (0.42) | RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9666465 | 0.82 | L3MBTL1 (0.38) | POLBSMN1; SMN2HTTRAB9APLCG1 | |
| SCHEMBL10975137 | 0.82 | HTT (0.39) | POLBSMN1; SMN2HTTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120613-A1 | Penem derivatives and precursors | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |