Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060245 | 0.78 | TDP1 (0.34) | — | |
| SCHEMBL11060249 | 0.78 | TDP1 (0.34) | — | |
| SCHEMBL8153165 | 0.73 | ACHE (0.53) | ACHEEPHX1BCHE | |
| SCHEMBL11873194 | 0.69 | EPHX1 (0.58) | ACHEEPHX1FAAH | |
| SCHEMBL16381789 | 0.69 | EPHX1 (0.58) | ACHEEPHX1FAAH | |
| SCHEMBL24977100 | 0.69 | EPHX1 (0.58) | ACHEEPHX1FAAH | |
| SCHEMBL19734493 | 0.69 | EPHX1 (0.58) | ACHEEPHX1FAAH | |
| SCHEMBL8012268 | 0.69 | ACHE (0.49) | ACHEEPHX1 | |
| SCHEMBL1577275 | 0.68 | FAAH (0.46) | ACHEEPHX1FAAH | |
| SCHEMBL3074530 | 0.67 | ACHE (0.50) | ACHEEPHX1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454134-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |