Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100119 | 0.89 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL201697 | 0.82 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11587907 | 0.82 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL14788107 | 0.82 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL20718744 | 0.78 | KMT2A (0.44) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL28238492 | 0.78 | UBE2T (0.58) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL12212189 | 0.76 | LIPG (0.66) | RAB9ANPC1SMN1; SMN2MAPTHTT | |
| SCHEMBL76564 | 0.76 | UBE2T (0.59) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30010006 | 0.74 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL11584549 | 0.74 | MAPT (0.44) | RAB9ANPC1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023022-B1 | COUMARINE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AS WELL AS THE INTERMEDIATE PRODUCTS USED PERSE AND THEIR UTILISATION FOR THE DYEING OR PRINTING OF TEXTILES | CIBA-GEIGY AG (CH) | 1984-04-11 | — | — | EP | disclosed |
| EP-0023022-A2 | Coumarine compounds, processes for their manufacture as well as the intermediate products used perse and their utilisation for the dyeing or printing of textiles | CIBA-GEIGY AG (CH) | 1981-01-28 | — | — | EP | disclosed |